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Domperidone is a prokinetic. It works on the region in the brain that controls vomiting. It also acts on the upper digestive tract to increase the movement of the stomach and intestines, allowing food to move more easily through the stomach.

Domperidone is an anti-sickness medicine. It helps you to stop feeling or being sick (nausea or vomiting). It can also be used to treat stomach pain if you're having end of life care (palliative care). Domperidone is sometimes used to increase milk supply.